★ Scientific Program
| BIT’s 10th Anniversary |
World DNA and Genome Day-2019 |
Theme: Exploration, Innovation, Breakthrough, Sharing |
Time: April 25-27, 2019 Place: Nanjing, China |
| Theme 3: Future Bioscientific Hub - Breakthroughs in Basic Research Today and Human Harmony Life Tomorrow Theme 3 covers major research trends nowdays in the diversified bioscientific fields, you are welcome to organizing your own sessions, we will provide you with best services at World DNA and Genome Day Event, each Hub may no just limited to one single sessions and may consist of multi-sessions and activities upon the demands: |
Program
Time: April 25-27, 2019
Venue: Nanjing International Youth Convention Hotel (NIYCH), Nanjing, China
| Registration |
| Time: 08:30-22:00, April 24, 2019 (Wednesday);Place: The Gate of Nanjing Hall, 5th Floor, NIYCH |
| Opening Ceremony |
| Time: 09:00-09:30, April 25, 2019 (Thursday); Place: Zhonghua Hall, 5th Floor, NIYCH |
| Nobel Laureate Forum & Keynote Forum | |
| Time: 09:30-12:05, April 25, 2019 (Thursday); Place: Zhonghua Hall, 5th Floor, NIYCH | |
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Moderator
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Dr. Ruiwen Zhang, Professor & Director, University of Houston, USA Dr. Guohua Zhou, Director, Jinling Hospital, School of Medicine Nanjing University, China |
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09:30-09:35
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Moderator's Introduction |
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09:35-10:05
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Title: Lessons from Yeas –Autophagy as a Cellular Recycling System Dr. Yoshinori Ohsumi, Honorary Professor, Institute of Innovative Research, Tokyo Institute of Technology, Japan Nobel Prize Laureate in Physiology or Medicine 2016 |
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10:05-10:35
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Title: Cell-free and GenoChemtic Strategies for Prototyping Parts, Biosynthetic Pathways and Xenobiotics Dr. Paul Freemont, Professor, Imperial College London, UK |
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10:35-11:05
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Title: Development of DNA Analysis Technologies - Micro Biopsy System for Site-Specific Tissue Analysis Dr. Hideki Kambara, President, Frontier Biosystems Inc.; Honorary Fellow, Hitachi Ltd.; Distinguished Guest Research Professor, Waseda University, Japan |
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11:05-11:35
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Title: Influence of the Gut Microbiome on Plasma Metabolite Patterns Dr. Bennard van Ravenzwaay, Senior Vice President, BASF SE, Germany |
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11:35-12:05
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Title: DNA- and RNA-Based Therapy: A 40-Year Learning Curve Dr. Ruiwen Zhang, Professor & Director, University of Houston, USA |
| Session 01: Biochemistry and Biophysics | |
| Time: 13:30-14:35, April 25, 2019 (Thursday); Place: Room 712, 7th Floor, NIYCH | |
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Chair
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Dr. Sheng-Lung Huang, Professor, National Taiwan University, Taiwan |
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13:30-13:35
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Chair's Introduction |
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13:35-13:55
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Title: The NMR Studies of Inhibition of Neuronal Cell Adhesion Molecule Polysialylation Dr. Guoping Zhou, Professor, Gordon Life Science Institute, USA; National Engineering Research Center for Non-food Biorefinery, Guangxi Academy of Sciences, China |
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13:55-14:15
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Title: Deep Learning on Cellular Resolution Optical Coherence Tomograms Dr. Sheng-Lung Huang, Professor, National Taiwan University, Taiwan |
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14:15-14:35
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Title: Accurate Analytic Solution of Chemical Master Equations for Gene Regulation Networks in a Single Cell Dr. Chin-Kun Hu, Professor, National Dong Hwa University, Taiwan |
| Session 02: Cell and Molecular Biology | |
| Time: 13:30-15:15, April 25, 2019 (Thursday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Robert Hasterok, Professor, University of Silesia in Katowice, Poland |
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Co-Chair
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Dr. Yong-Xiao Wang, Professor, Albany Medical College, USA |
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13:30-13:35
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Chair's Introduction |
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13:35-13:55
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Title: Liver Responds to Overnutrition and Remodels Whole-Body Lipid Deposition through Hepatocyte-Derived Exosomal miRNAs Dr. Chao-Jun Li, Professor, Model Animal Research Center and Medical School of Nanjing University, China |
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13:55-14:15
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Title: Dissecting the Chromosomal Composition of Mutagen-Induced Micronuclei in Brachypodium distachyon Using Multicolour FISH Dr. Robert Hasterok, Professor, University of Silesia in Katowice, Poland |
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14:15-14:35
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Title: Novel Cellular and Molecular Pathogenesis of Chronic Obstructive Pulmonary Disease Dr. Yong-Xiao Wang, Professor, Albany Medical College, USA |
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14:35-14:55
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Title: MicroRNA-574-3p Regulates Epithelial Mesenchymal Transition and Cisplatin Resistance via Targeting ZEB1 in Human Gastric Carcinoma Cells Dr. Qing Yang, Professor, Jilin University, China |
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14:55-15:15
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Title: New Anti Skin Aging Target SMC4 through Proteomic Study Coupled with Large Scale TCMs Screening Dr. Minhua Hong, Senior Manager, Shanghai Inoherb Co. Ltd. & Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, China |
| Session 03: System Biology, Genomics, Proteomics and Other Omics | |
| Time: 15:20-17:25, April 25, 2019 (Thursday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Zhihua Jiang, Professor, Washington State University, USA |
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15:20-15:25
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Chair's Introduction |
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15:25-15:45
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Title: Primate-Specific Long Non-coding RNA Genes: Causes of Human Disease, Targets for Post-genomic Therapeutics Dr. Leonard Lipovich, Associate Professor, Wayne State University, USA |
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15:45-16:05
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Title: Genome to Phenome: Amplification of DNA Function via Alternative Transcriptome Dr. Zhihua Jiang, Professor, Washington State University, USA |
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16:05-16:25
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Title: Proteome Quantification of Cotton Xylem Sap Suggests the Mechanisms of Potassium Deficiency-Induced Changes in Plant Resistance to Environmental Stresses Dr. Zhiyong Zhang, Director, Henan Institute of Science and Technology, China |
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16:25-16:45
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Title: Genetic Parts Screening and Artificial N-Glycosylation Motif Engineering for Heterologous Protein Production in Aspergillus Niger Dr. Jinxiang Zhang, Pricipal Investigator, Qingdao Vland Biotech Inc., China |
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16:45-17:05
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Title: Full-Length Transcriptome Sequences and the Identification of Putative Genes for Flavonoid Biosynthesis in Safflower Dr. Jin Pei, Professor, Chengdu University of Traditional Chinese Medicine, China |
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17:05-17:25
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Title: The Ethnic Differences of Plasma N-glycans among Croatian, Orcadian and Chinese Ms. Qiuyue Tian, Capital Medical University, China |
| Session 04: New Drug Discovery, Development and Delivery | |
| Time: 15:30-16:55, April 25, 2019 (Thursday); Place: Room 712, 7th Floor, NIYCH | |
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Chair
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Dr. Jing Li, Senior Vice President, WuXi Biologics, China |
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15:30-15:35
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Chair's Introduction |
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15:35-15:55
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Title: WuXiBody™, An Innovative and Potentially One-Size-Fit-All Bispecific Antibody Format to Open a New Gate for Therapeutic Bispecific Antibody Development Dr. Jing Li, Senior Vice President, WuXi Biologics, China |
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15:55-16:15
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Title: Unsaturated Mannuronate Oligosaccharide Ameliorates β-amyloid Pathology through Autophagy in Alzheimer's Disease Cells Dr. Xu Xu, Professor, Shenzhen University, China |
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16:15-16:35
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Title: A New Single Cell Isolation Technology for Single Cell Genomics Mr. Keli Chen, Chinese Leader, Namocell Inc., China |
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16:35-16:55
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Title: Vitamin K2 Promotes Glycolysis in Bladder Carcinoma Cells that Leads to AMPK-dependent Autophagic Cell Death Dr. Ling Hong, Professor, Huazhong University of Science and Technology, China |
| Session 05: Genetics and Epigenetics | |
| Time: 08:30-09:55, April 26, 2019 (Friday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Lolita Nikolova, Professor & CEO, Open Global Research Academy, USA |
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Co-Chair
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Dr. Sanjay Bidichandani, Professor & Chair, University of Oklahoma, USA |
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08:30-08:35
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Chair's Introduction |
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08:35-08:55
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Title: Relationship between Smoking and Protamines Genes Single Nucleotides Polymorphisms (SNPs) in Male Partners of Couples Undergoing Intracytoplasmic Sperm Injection (ICSI) Dr. Mohamad Eid Hammadeh, Professor, Saarland University, Germany |
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08:55-09:15
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Title: Cultural Genomics and Cultural Epigenetics Dr. Lolita Nikolova, Professor & CEO, Open Global Research Academy, USA |
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09:15-09:35
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Title: Epigenetic Silencing in Friedreich Ataxia Dr. Sanjay Bidichandani, Professor & Chair, University of Oklahoma, USA |
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09:35-09:55
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Title: Knowledge Discovery and Clinical Decision Support in the Big Data Era of Medicine Dr. Xueping Quan, Vice President, QIAGEN (Suzhou) Translational Medicine Co. Ltd., China |
| Session 06: Cancer Biology & Immuno-Oncology | |
| Time: 08:30-12:10, April 26, 2019 (Friday); Place: Room 716, 7th Floor, NIYCH | |
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Chair
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Dr. Simona Gurzu, Professor, University of Medicine, Pharmacy, Sciences and Technology of Tirgu-Mures, Romania |
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Co-Chair
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Dr. Yanping Zhang, Professor, The University of North Carolina at Chapel Hill, USA |
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08:30-08:35
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Chair's Introduction |
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08:35-08:55
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Title: The Role of Pathologist in Molecular Classification of Colorectal Cancer Dr. Ioan Jung, Professor & Head, University of Medicine and Pharmacy of Tirgu-Mures, Romania |
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08:55-09:15
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Title: The Role of Pathologist in Molecular Classification of Gastric Cancer Dr. Simona Gurzu, Professor, University of Medicine, Pharmacy, Sciences and Technology of Tirgu-Mures, Romania |
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09:15-09:35
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Title: One Stone Two Birds: Targeting Inflammation and Oncogene for Cancer Prevention and Therapy Dr. Ruiwen Zhang, Professor & Director, University of Houston, USA |
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09:35-09:55
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Title: 14-3-3 Proteins: Subcellular Localization and the Interaction with Rac1 Dr. Zhixiang Wang, Professor, University of Alberta, Canada |
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09:55-10:15
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Title: Epigenetic Regulation of Short and Long ncRNAs in Cancer Dr. Yangchao Chen, Associate Professor, The Chinese University of Hong Kong, Hong Kong, China |
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10:15-10:30
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Coffee Break |
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10:30-10:50
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Title: In Vivo Function and Regulation of Tumor Suppressor P53 and New Approaches to Cancer Drug Discovery Dr. Yanping Zhang, Professor, The University of North Carolina at Chapel Hill, USA |
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10:50-11:10
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Title: Toxicity of Hadrontherapy Versus Conventional Radiotherapy on Normal Tissues: DNA Damage, Oxidative Stress and Inflammation Dr. Carine Laurent, Group Leader, University of Caen-Normandy, France |
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11:10-11:30
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Title: Functional Role of a Novel Long Noncoding RNA TTN-AS1 in Esophageal Squamous Cell Carcinoma Progression and Metastasis Dr. Hanmei Xu, Professor, China Pharmaceutical University, China |
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11:30-11:50
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Title: Strategies to Develop Effective Therapeutic Antibodies - Studies of Anterior Gradient-2 (AGR2) Monoclonal Antibody Dr. Zhenghua Wu, Associate Professor, Shanghai Jiao Tong University, China |
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11:50-12:10
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Title: Vitamin K2 Promotes Glycolysis in Bladder Carcinoma Cells that Leads to AMPK-dependent Autophagic Cell Death Dr. Ling Hong, Professor, Huazhong University of Science and Technology, China |
| Session 07: Innovative Synthetic Biology Research and Application | |
| Time: 8:30-11:50, April 26, 2019 (Friday); Place: Room 715, 7th Floor, NIYCH | |
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Chair
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Dr. Xiaoli Xue, Professor, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, China |
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08:30-08:35
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Chair's Introduction |
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08:35-08:55
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Title: Prospective Applications of Synthetic Biology Dr. Li Zhu, Chief Strategy Officer, GenScript, China |
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08:55-09:15
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Title: Creating a Functional Single Chromosome Yeast Dr. Xiaoli Xue, Professor, Key Laboratory of Synthetic Biology, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, China |
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09:15-09:35
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Title: A Novel Method for Constructing Diverse Variant Libraries with Precise Codon Ratio Control Dr. Venus Liu, Senior Project Manager, GenScript, China |
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09:35-09:55
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Title: Automating Microbial Engineering Using Synthetic Biology, Robotics, And Mass Spectrometry Dr. Tong Si, Professor, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences, China |
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09:55-10:15
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Title: iGEM, Close Encounter of Synthetic Biology in Higher Education Dr. Ching Song, Professor, University of Science and Technology Beijing (USTB), China |
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10:15-10:30
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Coffee Break |
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10:30-10:50
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Title: Exploitation and Application of New Synthetic Biology Resources in Intestinal Microflora Dr. Yeshi Yin, Professor, Hunan University of Science and Engineering, China |
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10:50-11:10
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Title: The Importance of Wound Stress, A Micro-Environmental Factor, For Echinacoside Accumulation in Cistanche Deserticola Y.C. Ma Dr. Gaosheng Hu, Associate Professor, Shenyang Pharmaceutical University, China |
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11:10-11:30
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Title: Efficient Channeling of Carbon Sources to Pplysaccharides in a Spontaneous Mutant of Escherichia Coli Dr. Junsong Sun, Professor, Shanghai Advanced Research Institute, Chinese Academy of Sciences, China |
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11:30-11:50
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Title: The Novel Transcriptional Factor Modulates Antibiotic Biosynthesis in Actinomycetes by Opposing Response of Amino Acid Ligands Dr. Hang Wu, Associate Professor, Anhui University, China |
| Session 08: Computational and Integrative Structural Biology, and Bioinformatics | |
| Time: 08:30-09:55, April 26, 2019 (Friday); Place: Room 712, 7th Floor, NIYCH | |
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Chair
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Dr. Andrzej Kloczkowski, Professor, Nationwide Children's Hospital and The Ohio State University, USA |
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08:30-08:35
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Chair's Introduction |
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08:35-08:55
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Title: Machine Learning and Deep Learning for Prediction of Deleterious Mutations and for Phenotype Prediction Dr. Andrzej Kloczkowski, Professor, Nationwide Children's Hospital and The Ohio State University, USA |
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08:55-09:15
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Title: Absolute Measurement of Gene Expression by Selfie-PCR Dr. Petar Podlesniy, Institute for Biomedical Research of Barcelona, Spain |
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09:15-09:35
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Title: Impact of Technology: The Future of Learning about DNA and Genome Dr. Saied Ali Barzanian, Editor, ProQuest, USA |
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09:35:09:55
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Title: CNN-SVR Improves Prediction of CRISPR/Cas9 Guide RNA Activity Ms. Guishan Zhang, Sun Yat-Sen University, China |
| Session 09: New Biomedical Materials and Tissue Engineering | |
| Time: 10:30-11:15, April 26, 2019 (Friday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Jake (Jinkun) Chen, Professor & Director, Tufts University School of Medicine, USA |
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10:30-10:35
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Chair's Introduction |
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10:35-10:55
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Title: Tissue Engineering for Rotator Cuff Repair Dr. Chunfeng Zhao, Professor, Mayo Clinic, USA |
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10:55-11:15
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Title: A Novel Nanolipidoid-MicroRNA Formulation Promotes Bone Regeneration Dr. Jake (Jinkun) Chen, Professor & Director, Tufts University School of Medicine, USA |
| Session 10: Neurobiology and Neuroscience | |
| Time: 13:30-14:35, April 26, 2019 (Friday); Place: Room 712, 7th Floor, NIYCH | |
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Chair
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Dr. Wenhua Zheng, Professor, University of Macau, Macau, China |
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13:30-13:35
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Chair's Introduction |
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13:35-13:55
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Title: Dementia Prevention; Effect of Comorbid Diseases on Cognitive Decline Dr. Istvan J.E. Boksay, Professor, New York University, USA |
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13:55-14:15
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Title: The Neuronal Protective Effect of Artemether and Its Therapeutic Effect on the Alzheimer's Disease Dr. Wenhua Zheng, Professor, University of Macau, Macau, China |
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14:15-14:35
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Title: Acupuncture as Alternative Treatment of Autism Spectrum Diseases in Children Dr. Lili Luzina-Chju, TCM Center, Russia |
| Session 11: Immunology and Microbiology | |
| Time: 15:30-17:15, April 26, 2019 (Friday); Place: Room 712, 7th Floor, NIYCH | |
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Chair
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Dr. Giovanni Dondi dall'Orologio, Associate Professor, University of Bologna, Italy |
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15:30-15:35
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Chair's Introduction |
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15:35-15:55
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Title: Pilot Scale Phosphate Recovery with Microbial Electrolysis Cell Dr. Fabian Fischer, Professor, University of Applied Sciences and Arts Western Switzerland, Switzerland |
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15:55-16:15
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Title: A Randomized Cross-Over Trial for Evaluating Surgical Hand Disinfection Dr. Giovanni Dondi dall'Orologio, Associate Professor, University of Bologna, Italy |
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16:15-16:35
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Title: A Mechanism of Epstein-Barr Virus (EBV) Latency, Persistence and Tumorigenesis by EBV-Encoded Latent Membrane Protein 2A Dr. Makoto Fukuda, Lecturer, Tobu College of Medical Technology, Japan |
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16:35-16:55
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Title: Therapeutic Microbial Development through Protein-Based Synthetic Biology Approaches Dr. Chun-Loong Ho, Assistant Professor, Southern University of Science and Technology, China |
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16:55-17:15
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Title: N-glycosylation of human immunoglobulin G and rheumatoid arthritis risk in Han Chinese population: A Mendelian randomization study Dr. Youxin Wang, Professor, Capital Medical University, China |
| Session 12: Next Generation Diagnostics | |
| Time: 13:30-14:35, April 26, 2019 (Friday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Kailash Chadha, Associate Professor, Roswell Park Comprehensive Cancer Center, USA |
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13:30-13:35
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Chair's Introduction |
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13:35-13:55
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Title: KAPS-Biomarker for Early Diagnosis of Prostate Cancer Dr. Kailash C. Chadha, Associate Professor, Roswell Park Comprehensive Cancer Center, USA |
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13:55-14:15
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Title: In Silico Prioritization and Further Functional Characterization of SPINK1 Intronic Variants Dr. Wenbin Zou, Attending Physician, Changhai Hospital, China |
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14:15-14:35
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Title: The Effect of Rare Earth on the Microstructure, Corrosion Resistance and Heat Treatment Behavior of MgZnCa Alloys Developed for Orthopedic Applications Dr. Zhigang Xu, Senior Scientist, North Carolina A&T State University, USA |
| Session 13: Human Disease Biology, Smart Healthcare and Telemedicine | |
| Time: 08:30-09:35, April 27, 2019 (Saturday); Place: Room 713, 7th Floor, NIYCH | |
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Chair
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Dr. Aaron Han, Chief of Pathology, American Hospital, UAE |
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08:30-08:35
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Chair's Introduction |
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08:35-08:55
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Title: Personalized Medicine and the New Paradigm for Cancer Treatment: Experience from the Middle East Dr. Aaron Han, Chief of Pathology, American Hospital, UAE |
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08:55-09:15
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Title: Regulation of vascular BK Channel through AKAP150-mediated Akt/GSK3β signaling in Diabetes Mellitus Dr. Dai-Min Zhang, Professor, Nanjing First Hospital, Nanjing Medical University, China |
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09:15-09:35
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Title: WD40 Repeat and FYVE Domain Containing 3 (Wdfy3) Is Essential for Cardiac Development Dr. Hongxin Zhu, Associate Professor, Shanghai JiaoTong University, China |
Honorary Chairman
Professor Pingkai Ouyang, Academician, The Chinese Academy of Engineering, China
Concurrent Conference
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Hosting Organizations
 Information Research Center of International Talent, Ministry of Science and Technology, China |
 Jiangsu Pharmaceutical Association |
Academic Supporting
Organizations
Jiangsu Pharmaceutical Association Pharmacogenomic Professional Committee
Jiangsu Pharmaceutical Association Medical Biotechnology Professional Committee
Jiangsu Pharmaceutical Association Medicinal Chemistry Professional Committee
Operating Organizations
 Zhen-Ao Group Co., Ltd. |
 SHUANGDI, INC. |
 BIT Congress Inc. |
Official Travel Agency
Supporting Organization
European Medical Association
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